Vhf09301 details

Gene vhfRNAi AccessionVhf09301
Gene SymbolDLG1
Gene DescriptionDisks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene Name in PaperDLG1
GroupHost Factor
Ensembl Gene IDENST00000346964 ENST00000392382 ENST00000419354 ENST00000422288 ENST00000443183 ENST00000448528 ENST00000450955 ENST00000452595 
UniProt IDQ12959
Entrez Gene ID1739
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)