RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09251 |
| Gene Symbol | LAIR1 | |
| Gene Description | Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) (hLAIR1) (CD antigen CD305) | |
| Gene Name in Paper | LAIR1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000348231 ENST00000391742 ENST00000474878 ENST00000610549 ENST00000614937 ENST00000614946 ENST00000616612 ENST00000618434 ENST00000619717 ENST00000619817 ENST00000620077 ENST00000620357 ENST00000620726 ENST00000622097 | |
| UniProt ID | Q6GTX8 | |
| Entrez Gene ID | 3903 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |