RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09229 |
| Gene Symbol | AP4S1 | |
| Gene Description | AP-4 complex subunit sigma-1 (AP-4 adaptor complex subunit sigma-1) (Adaptor-related protein complex 4 subunit sigma-1) (Sigma-1 subunit of AP-4) (Sigma-4-adaptin) (Sigma4-adaptin) | |
| Gene Name in Paper | AP4S1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000216366 ENST00000313566 ENST00000334725 ENST00000542754 ENST00000554345 ENST00000616371 ENST00000622409 | |
| UniProt ID | Q9Y587 | |
| Entrez Gene ID | 11154 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |