Vhf09185 details

Gene vhfRNAi AccessionVhf09185
Gene SymbolCK054
Gene DescriptionEster hydrolase C11orf54 (EC 3.1.-.-)
Gene Name in PaperCK054
GroupHost Factor
Ensembl Gene IDENST00000331239 ENST00000354421 ENST00000528099 ENST00000528288 ENST00000540113 
UniProt IDQ9H0W9
Entrez Gene ID28970
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)