Vhf09155 details

Gene vhfRNAi AccessionVhf09155
Gene SymbolZSC23
Gene DescriptionZinc finger and SCAN domain-containing protein 23 (Zinc finger protein 390) (Zinc finger protein 453)
Gene Name in PaperZSC23
GroupHost Factor
Ensembl Gene IDENST00000289788 
UniProt IDQ3MJ62
Entrez Gene ID222696
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)