Vhf09127 details

Gene vhfRNAi AccessionVhf09127
Gene SymbolF181A
Gene DescriptionProtein FAM181A
Gene Name in PaperF181A
GroupHost Factor
Ensembl Gene IDENST00000267594 ENST00000556222 ENST00000557000 ENST00000557719 ENST00000611800 ENST00000617881 ENST00000620448 ENST00000626058 
UniProt IDQ8N9Y4
Entrez Gene ID90050
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)