Vhf09110 details

Gene vhfRNAi AccessionVhf09110
Gene SymbolRPH3L
Gene DescriptionRab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein)
Gene Name in PaperRPH3L
GroupHost Factor
Ensembl Gene IDENST00000323434 ENST00000331302 ENST00000536489 ENST00000608278 ENST00000608519 ENST00000618002 ENST00000632000 ENST00000632545 ENST00000632616 
UniProt IDQ9UNE2
Entrez Gene ID9501
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)