Vhf09103 details

Gene vhfRNAi AccessionVhf09103
Gene SymbolPSD1
Gene DescriptionPH and SEC7 domain-containing protein 1 (Exchange factor for ARF6) (Pleckstrin homology and SEC7 domain-containing protein 1)
Gene Name in PaperPSD1
GroupHost Factor
Ensembl Gene IDENST00000020673 ENST00000406432 ENST00000611678 
UniProt IDA5PKW4
Entrez Gene ID5662
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)