RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf09092 |
| Gene Symbol | HEM1 | |
| Gene Description | 5-aminolevulinate synthase, nonspecific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1) | |
| Gene Name in Paper | HEM1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000310271 ENST00000394965 ENST00000469224 ENST00000484952 | |
| UniProt ID | P13196 | |
| Entrez Gene ID | 211 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |