RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09045 |
Gene Symbol | NFYB | |
Gene Description | Nuclear transcription factor Y subunit beta (CAAT box DNA-binding protein subunit B) (Nuclear transcription factor Y subunit B) (NF-YB) | |
Gene Name in Paper | NFYB | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000240055 ENST00000551727 | |
UniProt ID | P25208 | |
Entrez Gene ID | 4801 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |