Vhf09032 details

Gene vhfRNAi AccessionVhf09032
Gene SymbolSPA9
Gene DescriptionSerpin A9 (Centerin) (Germinal center B-cell-expressed transcript 1 protein)
Gene Name in PaperSPA9
GroupHost Factor
Ensembl Gene IDENST00000298845 ENST00000337425 ENST00000380365 ENST00000424550 ENST00000448305 ENST00000538527 ENST00000546329 
UniProt IDQ86WD7
Entrez Gene ID327657
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)