Vhf09027 details

Gene vhfRNAi AccessionVhf09027
Gene SymbolLRAD4
Gene DescriptionLow-density lipoprotein receptor class A domain-containing protein 4
Gene Name in PaperLRAD4
GroupHost Factor
Ensembl Gene IDENST00000359446 ENST00000399848 ENST00000585931 ENST00000586765 ENST00000587757 ENST00000592991 
UniProt IDO15165
Entrez Gene ID753
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)