Vhf09018 details

Gene vhfRNAi AccessionVhf09018
Gene SymbolSTK19
Gene DescriptionSerine/threonine-protein kinase 19 (EC 2.7.11.1) (Protein G11) (Protein RP1)
Gene Name in PaperSTK19
GroupHost Factor
Ensembl Gene IDENST00000375331 ENST00000375333 ENST00000383327 ENST00000424104 ENST00000425138 ENST00000426802 ENST00000431383 ENST00000433397 ENST00000438256 ENST00000444147 ENST00000452688 
UniProt IDP49842
Entrez Gene ID8859
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)