RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf09015 |
Gene Symbol | RHOH | |
Gene Description | Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein) | |
Gene Name in Paper | RHOH | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000381799 ENST00000505618 ENST00000610353 ENST00000613272 ENST00000614836 ENST00000615083 ENST00000615577 ENST00000617441 ENST00000619474 ENST00000622175 | |
UniProt ID | Q15669 | |
Entrez Gene ID | 399 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |