Vhf09015 details

Gene vhfRNAi AccessionVhf09015
Gene SymbolRHOH
Gene DescriptionRho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene Name in PaperRHOH
GroupHost Factor
Ensembl Gene IDENST00000381799 ENST00000505618 ENST00000610353 ENST00000613272 ENST00000614836 ENST00000615083 ENST00000615577 ENST00000617441 ENST00000619474 ENST00000622175 
UniProt IDQ15669
Entrez Gene ID399
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)