Vhf08990 details

Gene vhfRNAi AccessionVhf08990
Gene SymbolSCMH1
Gene DescriptionPolycomb protein SCMH1 (Sex comb on midleg homolog 1)
Gene Name in PaperSCMH1
GroupHost Factor
Ensembl Gene IDENST00000326197 ENST00000337495 ENST00000361191 ENST00000361705 ENST00000372595 ENST00000372596 ENST00000372597 ENST00000397171 ENST00000397174 ENST00000402904 ENST00000456518 
UniProt IDQ96GD3
Entrez Gene ID22955
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)