Vhf08949 details

Gene vhfRNAi AccessionVhf08949
Gene SymbolSERC3
Gene DescriptionSerine incorporator 3 (Tumor differentially expressed protein 1)
Gene Name in PaperSERC3
GroupHost Factor
Ensembl Gene IDENST00000255175 ENST00000342374 
UniProt IDQ13530
Entrez Gene ID10955
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)