RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf08897 |
| Gene Symbol | H31 | |
| Gene Description | Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l) | |
| Gene Name in Paper | H31 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000356476 ENST00000359303 ENST00000369163 ENST00000612966 ENST00000613854 ENST00000614378 ENST00000614911 ENST00000616365 ENST00000618052 ENST00000621411 ENST00000634733 | |
| UniProt ID | P68431 | |
| Entrez Gene ID | 8350;8351;8352;8353;8354;8355;8356;8357;8358;8968 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |