Vhf08893 details

Gene vhfRNAi AccessionVhf08893
Gene SymbolHTAI2
Gene DescriptionOxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2)
Gene Name in PaperHTAI2
GroupHost Factor
Ensembl Gene IDENST00000419348 ENST00000421577 ENST00000443524 ENST00000451739 ENST00000530266 ENST00000532081 ENST00000532505 
UniProt IDQ9BUP3
Entrez Gene ID10553
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)