RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf08839 |
Gene Symbol | G3P | |
Gene Description | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-) | |
Gene Name in Paper | G3P | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000229239 ENST00000396858 ENST00000396859 ENST00000396861 ENST00000619601 | |
UniProt ID | P04406 | |
Entrez Gene ID | 2597 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |