Vhf08834 details

Gene vhfRNAi AccessionVhf08834
Gene SymbolNFU1
Gene DescriptionNFU1 iron-sulfur cluster scaffold homolog, mitochondrial (HIRA-interacting protein 5)
Gene Name in PaperNFU1
GroupHost Factor
Ensembl Gene IDENST00000303698 ENST00000394305 ENST00000410022 ENST00000462320 
UniProt IDQ9UMS0
Entrez Gene ID27247
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)