Vhf08831 details

Gene vhfRNAi AccessionVhf08831
Gene SymbolTICN3
Gene DescriptionTestican-3 (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3)
Gene Name in PaperTICN3
GroupHost Factor
Ensembl Gene IDENST00000357154 ENST00000357545 ENST00000421836 ENST00000502330 ENST00000504953 ENST00000506886 ENST00000510741 ENST00000511269 ENST00000511531 ENST00000512648 ENST00000512681 ENST00000541354 
UniProt IDQ9BQ16
Entrez Gene ID50859
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)