Vhf08825 details

Gene vhfRNAi AccessionVhf08825
Gene SymbolCRUM3
Gene DescriptionProtein crumbs homolog 3
Gene Name in PaperCRUM3
GroupHost Factor
Ensembl Gene IDENST00000308243 ENST00000356762 ENST00000598494 ENST00000600229 
UniProt IDQ9BUF7
Entrez Gene ID92359
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)