Vhf08823 details

Gene vhfRNAi AccessionVhf08823
Gene SymbolGBG5
Gene DescriptionGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Gene Name in PaperGBG5
GroupHost Factor
Ensembl Gene IDENST00000370641 ENST00000370645 
UniProt IDP63218
Entrez Gene ID2787
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)