Vhf08784 details

Gene vhfRNAi AccessionVhf08784
Gene SymbolS35D3
Gene DescriptionSolute carrier family 35 member D3 (Fringe connection-like protein 1)
Gene Name in PaperS35D3
GroupHost Factor
Ensembl Gene IDENST00000331858 
UniProt IDQ5M8T2
Entrez Gene ID340146
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)