RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf08775 |
Gene Symbol | RIC3 | |
Gene Description | Protein RIC-3 (Resistant to inhibitor of cholinesterase 3) | |
Gene Name in Paper | RIC3 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000309737 ENST00000335425 ENST00000343202 ENST00000419822 ENST00000425599 | |
UniProt ID | Q7Z5B4 | |
Entrez Gene ID | 79608 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |