Vhf08775 details

Gene vhfRNAi AccessionVhf08775
Gene SymbolRIC3
Gene DescriptionProtein RIC-3 (Resistant to inhibitor of cholinesterase 3)
Gene Name in PaperRIC3
GroupHost Factor
Ensembl Gene IDENST00000309737 ENST00000335425 ENST00000343202 ENST00000419822 ENST00000425599 
UniProt IDQ7Z5B4
Entrez Gene ID79608
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)