Vhf08764 details

Gene vhfRNAi AccessionVhf08764
Gene SymbolZNF48
Gene DescriptionZinc finger protein 48 (Zinc finger protein 553)
Gene Name in PaperZNF48
GroupHost Factor
Ensembl Gene IDENST00000320159 ENST00000612608 ENST00000613509 
UniProt IDQ96MX3
Entrez Gene ID197407
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)