Vhf08761 details

Gene vhfRNAi AccessionVhf08761
Gene SymbolMEIS2
Gene DescriptionHomeobox protein Meis2 (Meis1-related protein 1)
Gene Name in PaperMEIS2
GroupHost Factor
Ensembl Gene IDENST00000314177 ENST00000338564 ENST00000340545 ENST00000397620 ENST00000397624 ENST00000424352 ENST00000557796 ENST00000559085 ENST00000559561 ENST00000561208 
UniProt IDO14770
Entrez Gene ID4212
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)