Vhf08740 details

Gene vhfRNAi AccessionVhf08740
Gene SymbolPTOV1
Gene DescriptionProstate tumor-overexpressed gene 1 protein (PTOV-1) (Activator interaction domain-containing protein 2)
Gene Name in PaperPTOV1
GroupHost Factor
Ensembl Gene IDENST00000391842 ENST00000599732 ENST00000601675 
UniProt IDQ86YD1
Entrez Gene ID53635
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)