RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf08695 |
| Gene Symbol | DDAH2 | |
| Gene Description | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 (DDAH-2) (Dimethylarginine dimethylaminohydrolase 2) (EC 3.5.3.18) (DDAHII) (Dimethylargininase-2) (Protein G6a) (S-phase protein) | |
| Gene Name in Paper | DDAH2 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000375787 ENST00000375789 ENST00000375792 ENST00000383409 ENST00000400062 ENST00000400063 ENST00000411456 ENST00000413532 ENST00000413655 ENST00000414455 ENST00000424790 ENST00000426149 ENST00000427126 ENST00000430482 ENST00000434464 ENST00000437889 ENST00000443533 ENST00000444699 ENST00000447101 ENST00000451411 ENST00000454138 | |
| UniProt ID | O95865 | |
| Entrez Gene ID | 23564 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |