Vhf08681 details

Gene vhfRNAi AccessionVhf08681
Gene SymbolRHGBA
Gene DescriptionRho GTPase-activating protein 11A (Rho-type GTPase-activating protein 11A)
Gene Name in PaperRHGBA
GroupHost Factor
Ensembl Gene IDENST00000361627 ENST00000543522 ENST00000565905 ENST00000567348 ENST00000611363 ENST00000619401 ENST00000622253 ENST00000633634 
UniProt IDQ6P4F7
Entrez Gene ID9824
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)