RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf08652 |
| Gene Symbol | RO60 | |
| Gene Description | 60 kDa SS-A/Ro ribonucleoprotein (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (Ro 60 kDa autoantigen) (Sjoegren syndrome antigen A2) (Sjoegren syndrome type A antigen) (SS-A) (TROVE domain family member 2) | |
| Gene Name in Paper | RO60 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000367441 ENST00000367443 ENST00000367444 ENST00000367445 ENST00000367446 ENST00000400968 | |
| UniProt ID | P10155 | |
| Entrez Gene ID | 6738 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |