Vhf08628 details

Gene vhfRNAi AccessionVhf08628
Gene SymbolRAG2
Gene DescriptionV(D)J recombination-activating protein 2 (RAG-2)
Gene Name in PaperRAG2
GroupHost Factor
Ensembl Gene IDENST00000311485 ENST00000618712 
UniProt IDP55895
Entrez Gene ID5897
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)