RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf08621 |
| Gene Symbol | SC5AB | |
| Gene Description | Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium-dependent glucose cotransporter) (Sodium/glucose cotransporter KST1) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11) | |
| Gene Name in Paper | SC5AB | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000347898 ENST00000424767 ENST00000449109 ENST00000545376 ENST00000565769 ENST00000567758 ENST00000568579 ENST00000569071 | |
| UniProt ID | Q8WWX8 | |
| Entrez Gene ID | 115584 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |