Vhf08597 details

Gene vhfRNAi AccessionVhf08597
Gene SymbolKCND3
Gene DescriptionPotassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3)
Gene Name in PaperKCND3
GroupHost Factor
Ensembl Gene IDENST00000302127 ENST00000315987 ENST00000369697 
UniProt IDQ9UK17
Entrez Gene ID3752
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)