Vhf08585 details

Gene vhfRNAi AccessionVhf08585
Gene SymbolCF001
Gene DescriptionUncharacterized protein C6orf1 (Protein LBH)
Gene Name in PaperCF001
GroupHost Factor
Ensembl Gene IDENST00000394990 ENST00000468145 ENST00000476320 ENST00000481533 
UniProt IDQ86T20
Entrez Gene ID221491
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)