Vhf08561 details

Gene vhfRNAi AccessionVhf08561
Gene SymbolRCAN1
Gene DescriptionCalcipressin-1 (Adapt78) (Down syndrome critical region protein 1) (Myocyte-enriched calcineurin-interacting protein 1) (MCIP1) (Regulator of calcineurin 1)
Gene Name in PaperRCAN1
GroupHost Factor
Ensembl Gene IDENST00000313806 ENST00000381132 ENST00000399272 ENST00000443408 ENST00000482533 ENST00000487990 ENST00000620920 
UniProt IDP53805
Entrez Gene ID1827
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)