Vhf08551 details

Gene vhfRNAi AccessionVhf08551
Gene SymbolPKHG3
Gene DescriptionPleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)
Gene Name in PaperPKHG3
GroupHost Factor
Ensembl Gene IDENST00000247226 ENST00000394691 ENST00000471182 
UniProt IDA1L390
Entrez Gene ID26030
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)