Vhf08499 details

Gene vhfRNAi AccessionVhf08499
Gene SymbolMFF
Gene DescriptionMitochondrial fission factor
Gene Name in PaperMFF
GroupHost Factor
Ensembl Gene IDENST00000304593 ENST00000337110 ENST00000349901 ENST00000353339 ENST00000354503 ENST00000409565 ENST00000409616 
UniProt IDQ9GZY8
Entrez Gene ID56947
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)