RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf08492 |
| Gene Symbol | NR4A1 | |
| Gene Description | Nuclear receptor subfamily 4 group A member 1 (Early response protein NAK1) (Nuclear hormone receptor NUR/77) (Nur77) (Orphan nuclear receptor HMR) (Orphan nuclear receptor TR3) (ST-59) (Testicular receptor 3) | |
| Gene Name in Paper | NR4A1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000243050 ENST00000360284 ENST00000394824 ENST00000394825 ENST00000548232 ENST00000550082 | |
| UniProt ID | P22736 | |
| Entrez Gene ID | 3164 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |