RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf08489 |
| Gene Symbol | MAGI1 | |
| Gene Description | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3) | |
| Gene Name in Paper | MAGI1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000330909 ENST00000402939 ENST00000483466 ENST00000497477 ENST00000634409 ENST00000634774 ENST00000635378 ENST00000635471 | |
| UniProt ID | Q96QZ7 | |
| Entrez Gene ID | 9223 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |