RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf08473 |
| Gene Symbol | TPBG | |
| Gene Description | Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1) (Wnt-activated inhibitory factor 1) (WAIF1) | |
| Gene Name in Paper | TPBG | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000369750 ENST00000535040 ENST00000543496 ENST00000634817 ENST00000634826 ENST00000635036 | |
| UniProt ID | Q13641 | |
| Entrez Gene ID | 7162 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |