Vhf08471 details

Gene vhfRNAi AccessionVhf08471
Gene SymbolC56D2
Gene DescriptionCytochrome b561 domain-containing protein 2 (Putative tumor suppressor protein 101F6)
Gene Name in PaperC56D2
GroupHost Factor
Ensembl Gene IDENST00000232508 ENST00000418577 ENST00000424512 ENST00000425346 
UniProt IDO14569
Entrez Gene ID11068
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)