Vhf08442 details

Gene vhfRNAi AccessionVhf08442
Gene SymbolPGS2
Gene DescriptionDecorin (Bone proteoglycan II) (PG-S2) (PG40)
Gene Name in PaperPGS2
GroupHost Factor
Ensembl Gene IDENST00000052754 ENST00000393155 ENST00000420120 ENST00000425043 ENST00000441303 ENST00000456569 ENST00000547568 ENST00000552962 
UniProt IDP07585
Entrez Gene ID1634
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)