Vhf08433 details

Gene vhfRNAi AccessionVhf08433
Gene SymbolHLAF
Gene DescriptionHLA class I histocompatibility antigen, alpha chain F (CDA12) (HLA F antigen) (Leukocyte antigen F) (MHC class I antigen F)
Gene Name in PaperHLAF
GroupHost Factor
Ensembl Gene IDENST00000259951 ENST00000334668 ENST00000359076 ENST00000376848 ENST00000376861 ENST00000383515 ENST00000420067 ENST00000434407 ENST00000440590 
UniProt IDP30511
Entrez Gene ID3134
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)