Vhf08427 details

Gene vhfRNAi AccessionVhf08427
Gene SymbolHMOX2
Gene DescriptionHeme oxygenase 2 (HO-2) (EC 1.14.14.18)
Gene Name in PaperHMOX2
GroupHost Factor
Ensembl Gene IDENST00000219700 ENST00000398595 ENST00000406590 ENST00000414777 ENST00000458134 ENST00000570646 ENST00000575120 ENST00000612525 ENST00000615778 ENST00000619528 ENST00000619913 ENST00000620445 ENST00000621065 ENST00000622146 ENST00000631540 ENST00000631677 ENST00000632458 ENST00000633319 
UniProt IDP30519
Entrez Gene ID3163
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)