RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf08427 |
Gene Symbol | HMOX2 | |
Gene Description | Heme oxygenase 2 (HO-2) (EC 1.14.14.18) | |
Gene Name in Paper | HMOX2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000219700 ENST00000398595 ENST00000406590 ENST00000414777 ENST00000458134 ENST00000570646 ENST00000575120 ENST00000612525 ENST00000615778 ENST00000619528 ENST00000619913 ENST00000620445 ENST00000621065 ENST00000622146 ENST00000631540 ENST00000631677 ENST00000632458 ENST00000633319 | |
UniProt ID | P30519 | |
Entrez Gene ID | 3163 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |