Vhf08394 details

Gene vhfRNAi AccessionVhf08394
Gene SymbolSUGP1
Gene DescriptionSURP and G-patch domain-containing protein 1 (RNA-binding protein RBP) (Splicing factor 4)
Gene Name in PaperSUGP1
GroupHost Factor
Ensembl Gene IDENST00000247001 ENST00000588731 
UniProt IDQ8IWZ8
Entrez Gene ID57794
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)