Vhf08385 details

Gene vhfRNAi AccessionVhf08385
Gene SymbolTRI27
Gene DescriptionZinc finger protein RFP (EC 6.3.2.-) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)
Gene Name in PaperTRI27
GroupHost Factor
Ensembl Gene IDENST00000377194 ENST00000377199 ENST00000400720 ENST00000412687 ENST00000417660 ENST00000427689 ENST00000431123 ENST00000435528 ENST00000437160 ENST00000452265 
UniProt IDP14373
Entrez Gene ID5987
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)