Vhf08357 details

Gene vhfRNAi AccessionVhf08357
Gene SymbolZN397
Gene DescriptionZinc finger protein 397 (Zinc finger and SCAN domain-containing protein 15) (Zinc finger protein 47)
Gene Name in PaperZN397
GroupHost Factor
Ensembl Gene IDENST00000261333 ENST00000330501 ENST00000585800 ENST00000591206 
UniProt IDQ8NF99
Entrez Gene ID84307
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)