Vhf08356 details

Gene vhfRNAi AccessionVhf08356
Gene SymbolF189B
Gene DescriptionProtein FAM189B (Protein COTE1)
Gene Name in PaperF189B
GroupHost Factor
Ensembl Gene IDENST00000350210 ENST00000361361 ENST00000368368 ENST00000572488 ENST00000574749 ENST00000575430 
UniProt IDP81408
Entrez Gene ID10712
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)