Vhf08286 details

Gene vhfRNAi AccessionVhf08286
Gene SymbolMOBP
Gene DescriptionMyelin-associated oligodendrocyte basic protein
Gene Name in PaperMOBP
GroupHost Factor
Ensembl Gene IDENST00000311042 ENST00000383754 ENST00000415443 ENST00000420739 ENST00000424090 ENST00000428261 ENST00000441980 ENST00000442631 ENST00000447324 ENST00000452959 
UniProt IDQ13875
Entrez Gene ID4336
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)